whenever I see threads like this, i like to reflect on youtube...
https://www.youtube.com/watch?v=7pdWAcK6Eh8
Since there is no right answer, as each have there own merits. Me, personally, i'm an OG frame guy, but i'd do a frame swap in a second if the scenario was right.
I guess my advice is look at the 3 areas of any project: 1. Time 2. Cost and 3. Scope. Find the formula that best works for you.
Then go to a few car shows this summer, find some trucks you like and see what they did and see if that aligns with the aspects of your project above.
When you've got all that figured out, stop on back here, lurk around, say hi, and keep us posted on what you do
Lastly, have the flexibility to change any of the 3 aspects as life changes. From personal experience, i can tell you that on the short-term, my time availablity has shrunk significantly, but i'm ok with that.
good luck!