Main harness power

[kvjb]

Here is a quick question for the electrical gurus. I'm putting an aftermarket harness in my '51 and I'm wondering if it makes any difference if I run the main harness power lead from the alternator post instead of directly from the battery? the alternator post is closer and provides a more straightforward connection to my fusebox. I will have a 6 gauge wire from alternator to the starter and heavy gauge wire back to the battery. I plan to run the fusebox power wire through a fusible link either way. Any insight is appreciated.
Thanks