1 ton axels on 1/2 ton frame...problem?

[500HP/SB]

I had never given this much thought untill a friend brought it up. i plan on putting a 14bFF/dana60 or 14/44 combo under my 1/2 ton truck to help my piece of mind due to my heavy right foot, 35's and 450+hp.

Is there a potential problem with all that wieght/mass and the 1/2 ton frame holding it together? Can the frame handle the tortional flex and all of the new strains? I know people put big axels under thier litle toyotas and stuff so i dont see it being a big deal.

Thanks